Mononuclear cell tissue factor : cell of origin and requirements for
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Mononuclear cell tissue factor: cell of origin and requirements for activation.
Human mononuclear leukocytes generate the procoagulant material tissue factor (TF) following stimulation by endotoxin, mitogens, or antigens in vitro. We have examined tissue-factor generation by mononuclear cell subpopulations prepared in a variety of ways in order to determine the cell of origin of mononuclear cell TF and the conditions necessary for maximal in vitro TF generation. We have al...
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